عنوان صفحه
فصل اول: مقدمه و مروري بر مطالعات مشابه 1
1-1- خانواده پسود و موناداسه آ 2
1-2-1- خصوصیات مورفولوژیک P. aeruginosa 5
1-2-3- هوازیهای اجباریObligate aerobes 5
1-2-8- شاخصهای بیماریزایی در P. aeruginosa 11
1-2-8-2- آلژینات (Alginate) 12
1-2-8-4- پروتئازهای خارج سلولی 13
1-2-9- توکسینهای خارج سلولی 16
1-2-10- لوکوسیدین با وزن ملکولی بالا 17
1-2-15- سیستم ترشحی نوع III 18
1-2-17- بیماریهای ناشی از P. aeruginosa 20
1-2-17-4- عفونتهای مجرای تنفسی 21
1-2-17-5- عفونتهای استخوان و مفصل 22
1-2-17-6- عفونتهای سیستم عصبی مرکزی 22
1-2-17-7- عفونتهای دستگاه گوارش 22
1-2-17-8- عفونتهای پوست و بافت نرم 23
1-2-17-9- عفونتهای دستگاه ادارای 24
1-2-17-11- عفونتهای استخوان و مفصل 24
1-2-17-12- عفونتهای سیستم عصبی مرکزی 24
1-2-17-13- اندوکاردیت عفونی 25
1-2-17-14- عفونتهای مجرای تنفسی 25
1-2-17-15- عفونت پوست و بافتهای نرم 26
1-2-17-16- عفونتهای ادراری 26
1-2-19- شيوع مقاومت متالوبتالاکتامازها 27
1-2-20- انواع تيپهای متالوبتالاکتاماز 28
1-2-21- The Imipenemase(IMP) Type 28
1-2-22- The Veronese Imipenemase (VIM) Type 28
1-2-23- New Delhi Metalo β-lactamase-1 (NDM-1) Type 28
1-2-24- ديگر تيپهای متالوبتالاکتاماز 29
1-2-24-1- روشهای تشخيص متالوبتالاکتاماز 29
1-2-24-2- سنجس حساسيت) آنتی بيوگرام) 29
1-2-24-3- روش E.Test به وسيله نوار MBL 30
2-1 بیان مسئله و اهمیت موضوع 35
2-5-2- مکانکی آگار(Mac Conkey agar) 37
2-5-4- روش آماده سازی معرف کواکس جهت تست اندول 39
2-6-2- تعیین آنزیم متالوبتالاکتاماز 43
2-6-4- محدودیت و مشکلات اجرایی طرح 44
فصل چهارم: بحث، نتیجه گیری و پیشنهادات 69
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